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KMID : 0370219840280050293
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Yakhak Hoeji
1984 Volume.28 No. 5 p.293 ~ p.297
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Apparent pKa and Partition Coefficient of Tranylcypromine
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강건일/Kang GI
정순영/Chung SY
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Abstract
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The pKa’’ of tranylcypromine was determined by potentiometric titration and ultraviolet spectrophotometric method and found to be 8.08 and 8.15, respectively. The Papp of tranylcypromine between n-heptane and aqueous buffer solution was measured to be 0.90 at pH 7.48 and 4.50 for Pm. The pKa’’ of tranylcypromine obtained by means of the partition method was 8.13.
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